EXUBERA® Official Site – EXUBERA Home Page – Learn About A Diabetes Treatment Option

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Availability of EXUBERA® (insulin human [rDNA origin]) Inhalation Powder

As previously announced, Pfizer stopped marketing Exubera in January 2008 because it did not meet customers’ needs or financial expectations. No new supplies of Exubera have been manufactured in 2008, and remaining supplies will expire soon. As a result, Exubera will no longer be available as of September 1, 2008.

What do you need to know?

Those pharmacies that still have Exubera stocks
will stop dispensing Exubera as of 01 September
2008. In addition, the Exubera Extended
Transition Program will be discontinued as of 01
September 2008.

What does this mean for you?

You will no longer be able to obtain Exubera after
September 1, 2008. If your pharmacy runs out of
Exubera, you should contact your physician as
soon as possible to discuss other options for
lowering your blood sugar. You should not stop
taking Exubera without first discussing this with
your doctor.

This information does not take the place of talking with your doctor about your condition or treatment. Please speak with your doctor about any questions or concerns you may have.

Sincerely,

       Rochelle L. Chaiken, MD
       Vice President,
       Global Medical Cardiovascular and Metabolic Disease
       Pfizer Inc

Important Safety Information About Exubera® (insulin human [rDNA origin]) Inhalation Powder

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EXUBERA is a prescription medicine that you breathe in through your mouth using the EXUBERA^® Inhaler. It is a short-acting insulin that helps to control high blood sugar in adults with diabetes. If you have Type 1 diabetes, you will have to take longer-acting insulin in addition to EXUBERA. If you have Type 2 diabetes, you may use EXUBERA by itself, or with diabetes pills. Some patients with Type 2 diabetes will need to take some longer-acting insulin in addition to EXUBERA.

Important Safety Information

EXUBERA may lower your lung function, so you will need to take a breathing test before you start treatment and, from time to time, as you keep taking EXUBERA.

You should not take EXUBERA if you have an unstable or poorly controlled lung disease (such as unstable or poorly controlled asthma, chronic obstructive pulmonary disease) or if you smoke, start smoking, or quit smoking less than 6 months ago. You should not take EXUBERA if you are under 18 years of age or if you are allergic to insulin or any of the inactive ingredients in EXUBERA.

Tell your health care provider about all your health and medical conditions, including if you have any lung disease or breathing problems, if you are pregnant, or plan to become pregnant.

As with all forms of insulin, a possible side effect of EXUBERA is low blood sugar (hypoglycemia), which can be mild to severe. It is important to check your blood sugar as your health care provider has advised you. Other common side effects are cough, dry mouth and chest discomfort.

For more information about EXUBERA , please see the Medication Guide and the Full Prescribing Information.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a health care provider. All decisions regarding patient care must be made with a health care provider, considering the unique characteristics of the patient.

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